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Pros and Cons of Snus and Nicotine Pouches in Italy Snus and nicotine pouches are relatively new products in the Italian market and have gained popularity among tobacco users

Tobacco substances undergo first-pass metabolism in the liver, exposing the organ to a complex array of over 4000 toxic chemicals, including nicotine, nitrosamines, aromatic hydrocarbons, and various carcinogens [2,3,4]

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